MRFF – CTA Initiative – 2025 Clinical Trials Activity Grant Opportunity
Tender ID: 595771
Tender Details
Tender Description
The Medical Research Future Fund (MRFF) Clinical Trials Activity Initiative aims to:
- improve the evidence base supporting clinical care
- help patients access trials relevant to their health circumstances
- enable researchers to bring international trials to Australian patients.
The objective of this grant opportunity is to provide grants of financial assistance to support medical research and medical innovation projects that:
- Stream 1 (Incubator): conduct a pilot study to assess the feasibility of a new clinical trial for one or more treatments and/or management strategies for a rare cancer, rare disease and/or unmet need.
- Stream 2 (Targeted Call for Research): conduct a clinical trial of one or more treatments and/or management-based interventions for rare cancers, rare diseases and/or unmet need.
- Stream 3 (Targeted Call for Research): conduct a clinical trial that supports the delivery of effective and high value care by targeting evidence gaps of value to health technology assessment processes in Australia.
- Stream 4 (Targeted Call for Research): conduct a prevention clinical trial aimed at reducing the risk, onset or progression of disease through early intervention strategies.
The intended outcome of the research is to improve the health and wellbeing of Australians by investing in new clinical trials that support increased access to high-quality, evidence-based and effective health care.
Applicants to this grant opportunity must propose research that addresses one of the four Streams of research.
This grant opportunity is being administered by NHMRC on behalf of the Australian Government Department of Health, Disability and Ageing.
Further information on the Medical Research Future Fund is available from the Department of Health, Disability and Ageing's website.
A list of Eligible Organisations can be found on the NHMRC List of MRFF Eligible Organisations webpage
Eligibility:
Applications will only be accepted from approved MRFF Eligible Organisations. A list of approved MRFF Eligible Organisations is available from the MRFF Eligible Organisations List on the NHMRC website.
Applications must satisfy all the requirements set out in the Medical Research Future Fund – Clinical Trials Activity Initiative - 2025 Clinical Trials Activity Grant Opportunity Guidelines.
Grant Activity Timeframe:
Within 7 years of execution of the grant schedule.
Total Amount Available (AUD):
$61,000,000.00
Estimated Grant Value (AUD):
From $0.00 to $5,000,000.00
Instructions for Application Submission:
Applicants are advised to read the Grant Guidelines thoroughly and liaise with the MRFF Eligible Organisation that will submit the application to identify any specific requirements that the Organisation might have.
Applications must be submitted electronically using NHMRC’s online granting system (Sapphire).
Other Instructions:
Minimum Data closes at 5:00pm (ACT Local Time) on 4 March 2026.
Questions should be submitted no later than 1:00pm (ACT Local Time) on 25 March 2026.
Location
New South Wales : Central West : Far North Coast : Far West : Hunter : Illawarra : Mid North Coast : Murray : New England : Orana : Riverina : Southern Highlands : Sydney
Queensland : Cairns & Far North Queensland : Gladstone : Mackay Whitsunday Region : Mount Isa & North West Region : Rockhampton : South East Queensland : South West & Darling Downs : The Central West : Townsville : Wide Bay Burnett
Victoria : Barwon South West : Gippsland : Grampians : Hume : Loddon Mallee : Melbourne
South Australia : Adelaide : Eyre & Western : Far North : Fleurieu & Kangaroo Island : Limestone Coast : Murray & Mallee : York & Mid North
Northern Territory : Barkly : Big Rivers : Central Australia : East Arnhem : Greater Darwin : Top End
Australian Capital Territory
Tasmania
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